What are possible side effects of using
Propranolol HCl?
Propranolol is reported to be generally
well-tolerated. Rare or mild adverse reactions include:
nausea
abdominal cramps
blurred vision
decreased concentration
insomnia
hallucinations
nervousness or excitement
fatigue
slow heart rate
erectile dysfunction
What is the recommended dose of
Propranolol HCl?
In children, the total initial daily dose may be
calculated on the basis of 0.5 mg per 1 kg of body weight
(about 0.2 mg per 1 lb). The maximum daily dose should
not exceed 8 mg per 1 kg (about 3.5 mg per 1 lb) of body
weight.
In adults, the minimum sufficient daily dose is 20 mg,
while the maximum dose should not exceed 320 mg daily.
For hypertension and migraine prophylaxis, the usual starting
dose is 40 mg two times a day, with the usual effective dose
ranging from 160 to 240 mg daily. For tachyarrhythmia, anxiety
and hyperthyroidism, the dose is 10 to 40 mg three to four
times a day.
The drug is taken before meals or at bedtime.
When should Propranolol HCl be
avoided?
Propranolol HCl should not be used
in patients who have asthma
in patients with 2nd and 3rd degree heart block or uncontrolled congestive heart failure
in patients with bradycardia (less than 60 heart beats a minute)
in patients with severe hypotension
in patients allergic to Propranolol hydrochloride
while drinking alcohol
Propranolol HCl should be used with caution in
patients with:
bronchitis, emphysema, or other breathing disorders
diabetes
low blood pressure
a heart block
liver or kidney disease
depression
myasthenia gravis (a muscle disorder)
Combining Propranolol HCl with
other medications.
Propranolol may cause unwanted reactions if combined
with:
clonidine (Catapres)
digitalis (Lanoxin)
dobutamine (Dobutrex)
haloperidol (Haldol)
isoproterenol (Isuprel)
blood thinners (e.g., warfarin (Coumadin))
antidepressants (e.g., amitriptyline (Elavil,
Etrafon), clomipramine (Anafranil), desipramine
(Norpramin), imipramine (Janimine, Tofranil))
MAOIs (e.g., isocarboxazid (Marplan), phenelzine
(Nardil), rasagiline (Azilect), selegiline (Eldepryl,
Emsam), or tranylcypromine (Parnate))
aspirin and other non-steroidal anti-inflammatory
drugs (e.g., ibuprofen (Motrin, Advil), naproxen (Aleve,
Naprosyn), diclofenac (Cataflam, Voltaren), etodolac
(Lodine), indomethacin (Indocin), ketoprofen (Orudis))
doxazosin (Cardura), prazosin (Minipress), terazosin
(Hytrin)
other heart medications (e.g., nifedipine (Procardia,
Adalat), reserpine (Serpasil), diltiazem (Cartia,
Cardizem), or verapamil (Calan, Verelan, Isoptin))
amiodarone (Cordarone, Pacerone), propafenone (Rythmol),
quinidine (Quinaglute, Quinidex, Quin-Release)
ACE inhibitors (e.g., benazepril (Lotensin),
captopril (Capoten), fosinopril (Monopril), enalapril
(Vasotec), lisinopril (Prinivil, Zestril), moexipril
(Univasc), perindopril (Aceon), quinapril (Accupril),
ramipril (Altace), or trandolapril (Mavik)
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