Pliva's Oxybutynin Chloride


Oxybutynin Effects and Usage




Oxybutynin - generic Ditropan / Oxytrol

What kind of medication is Oxybutynin?

Oxybutynin chloride is used to treat frequent or urgent urination, incontinence (urine leakage), and increased night-time urination. The medication works by reducing muscle spasms of the bladder and urinary tract.

When distributed by Pliva Pharmaceuticals, Inc., Oxybutynin is available on the market as Pliva 456 5 mg pills.

Oxybutynin is also marketed under various trade names that include Ditropan and Oxytrol (transdermal patches).

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What are possible side effects of using Oxybutynin?

Adverse reactions may include:

  • dry mouth
  • blurred vision
  • constipation
  • nausea
  • headache
  • dizziness
  • drowsiness
  • fatigue
  • extreme thirst
  • stomach pain

  • What is the recommended dose of Oxybutynin?

  • In adults, the normal dose is 5 mg two or three times a day. The total maximum dose should not exceed 20 mg.

  • In children of 5 years and older, the normal dose is 5 mg two times daily. The total maximum dose should not exceed 15 mg.

  • In children under 5 years, Oxybutynin is rarely administered. If required, the dose must be determined by the physician.


  • When should Oxybutynin be avoided?

    Oxybutynin should not be used

  • in patients allergic to Oxybutynin
  • in patients with untreated or uncontrolled narrow-angle glaucoma
  • in patients suffering from a blockage in the digestive tract
  • in patients unable to urinate

  • Oxybutynin should be used with caution in patients with:

  • hypertension
  • an enlarged prostate
  • kidney or liver problems
  • ulcerative colitis
  • gastroesophageal reflux disease (GERD)
  • slow digestion
  • myasthenia gravis (a muscle disorder)

  • Oxybutynin should not be be combined with:

  • other bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), tolterodine (Detrol), or solifenacin (Vesicare)

  • glycopyrrolate (Robinul)

  • flecainide (Tambocor)

  • mepenzolate (Cantil)

  • thioridazine (Mellaril)

  • HIV /AIDS medicine (e.g., nelfinavir (Viracept) or ritonavir (Norvir)

  • antibiotics

  • antifungal medication (e.g., itraconazole (Sporanox) or ketoconazole (Nizoral)

  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop)

  • bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva)

  • irritable bowel medications (e.g., dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine)

  • antidepressant (e.g., amitriptyline (Elavil, Etrafon), fluoxetine (Prozac), fluvoxamine (Luvox), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), etc) because they may increase drowsiness caused by Oxybutynin.