Pliva's Metoclopramide


Metoclopramide Effects and Usage




Metoclopramide - generic Reglan / Maxolon

What kind of medication is Metoclopramide?

Metoclopramide is a gastrointestinal stimulant and antinauseant used to treat gastroesophageal reflux disease (GERD) and certain digestive problem in diabetic patients. It relieves nausea, heartburn, a feeling of fullness after meals, and loss of appetite.

When distributed by Pliva Pharmaceuticals, Inc., Metoclopramide is available on the market as Pliva 517 5 mg and Pliva 430 10 mg pills.

The medication is also marketed under various trade names that include Reglan and Maxolon.

order metoclopramide pills

What are possible side effects of using Metoclopramide?

Adverse reactions are rare, but they may include:

  • abdominal cramps
  • seizures
  • dark urine
  • difficulty in breathing or swallowing
  • headache
  • dizziness
  • fast or irregular heartbeat
  • increase in blood pressure
  • sweating
  • itching and skin rash
  • If overdosed, Metoclopramide may cause confusion or drowsiness.

    What is the recommended dose of Metoclopramide?

  • In adults, the dose is 10 to 15 mg up to four times a day. The medication is taken about half an hour before the expected symptoms begin.

  • In children, the dose must be determined by the physician.


  • When should Metoclopramide be avoided?

    Metoclopramide should not be used

  • in patients allergic to Metoclopramide
  • in epileptic patients
  • in patients suffering from bleeding, blockage, or perforation in the stomach or intestines
  • in patients suffering from tumors on your adrenal gland

  • Metoclopramide should be used with caution

  • by pregnant or breast-feeding women
  • by patients who have a history of mental or mood problems
  • by patients who have a history of asthma, heart failure, hypertension, diabetes, Parkinson disease, blood problems, kidney or liver problems, or breast cancer

  • Metoclopramide should not be be combined with:

  • phenothiazines (t.g., chlorpromazine (Thorazine, Largactil)) becasue they may cause abnormal, involuntary muscle movements of the head, neck, or limbs.

  • MAOIs (e.g., phenelzine (Nardil)) because of the increased risk of high blood pressure and seizures

  • hyoscyamine (Levsin) and other anticholinergic medicines because they may increase the effects of Metoclopramide

  • sedatives and narcotic pain relivers because their side effects can be dangerously increased by Metoclopramide

  • Cabergoline (Dostinex, Cabaser), digoxin (Lanoxin), or pergolide (Permax) because their effectiveness may be decreased by Metoclopramide