Desyrel - Trazodone Hydrochloride

Desyrel Effects and Usage

Generic Desyrel - Trazodone HCl

What kind of medication is Desyrel?

Desyrel is an antidepressant medication with anxiolytic and hypnotic properties. It is mainly used to treat depression, but may also be used as an anti-anxiety medication (relieving sleeplessness and tension) and as a reliver for chronic pain.

A generic version of Desyrel is manufactured by Pliva Pharmaceuticals, Inc., as Pliva 433 50 mg Pliva 434 100 mg and Pliva 441 150 mg pills.

The generic name for Desyrel is Trazodone hydrochloride.

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What are possible side effects of using Desyrel?

Possible adverse reactions include:

  • drowsiness
  • dry mouth
  • nausea and/or vomiting
  • headache
  • tremor
  • irregular heartbeat
  • dizziness
  • fatigue
  • confusion
  • memory loss

  • What is the recommended dose of Desyrel?

  • In adults, the initial dose of Desyrel is 75 mg taken twice a day. The doses may be increased by 25 mg every three to four days. The normal maximum dose should not exceed 200 mg taken twice daily. Severely depressed patients may be given up to 200 mg three times a day.

  • In children, Desyrel is usually not recommended. If required, the dose must be determined by the doctor.
  • The medication should be taken after having a meal.

    When should Desyrel be avoided?

    Desyrel should not be used

  • in patients allergic to Trazodone hydrochloride

  • Desyrel should be used with caution in:

  • pregnant women and breast-feeding mothers
  • patients with a history of drug abuse or suicidal thoughts
  • patients with schizophrenia, or other psychiatric illness
  • patients with heart problems

  • Combining Desyrel with other medications.

    Desyrel should be taken with caution in combination with:

  • an HIV medicine (e.g., indinavir (Crixivan) or ritonavir (Norvir))

  • antifungal medications (e.g., ketoconazole (Nizoral) or itraconazole (Sporanox))

  • digoxin (Lanoxin, Lanoxicaps)

  • seizure medicine such as carbamazepine (Carbatrol, Tegretol) or phenytoin (Dilantin)

  • warfarin (Coumadin)

  • MAOIs (e.g., isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate)) within the past 14 days of using any of them last

  • An overdose of Desyrel can be fatal if it is combined with alcohol, barbiturates (e.g., phenobarbital (Luminal)), or sedatives such as diazepam (Valium).